He was born on 2 August, 1952, in the town of Shu in the Zhambyl region. He is a doctor of political sciences, professor.
He began his working life in 1969 in the high-school named after S.Seifullin in the town of Shu.
He graduated from the Kazakh pedagogical institute named after Abay (1974), Almaty Institute of National Economy (1985), Almaty Highest Party School (1990).
From 1973 through 1976 he was a Deputy Secretary, Secretary of Komsomol Committee by the Kazakh Pedagogical Institute.
From 1976 through 1983 he worked as Secretary of the Frunze district Executive Committee, regional Committee, Head of division of the republican Komsomol’s Central Committee.
In 1983-1990 he worked in Alma-Ata regional Committee, Central Committee of Kazakhstan’s Komsomol.
In 1990-1996 he served as Head of the General Department of the Presidential Office and Minister Cabinet, Head of the Document Processing Department of the President’s Executive Office.
From 1996 he worked as Chairperson of the Chancellery, Head of the Chancellery of President.
M.Kasymbekov published more than 100 scientific articles, he is an author, co-author and also a compiler of 25 books. He has been awarded the Order of Kurmet (Honour), Order of Barys of III degree, 7 medals, "Kazakhstan Respublikasynyn Tungysh Presidenty Nursultan Nazarbayev" (First President of the Republic of Kazakhstan Nursultan Nazarbayev) Award. He is also State Prize winner in science, technics and education.